• Vision

    Collective Intelligence Fostering Innovative Ideas

    READ MORE

  • Vision

    Collective Intelligence Fostering Innovative Ideas

    READ MORE

  • Vision

    Collective Intelligence Fostering Innovative Ideas

    READ MORE


Correlates of immune protection

During the viral infection, a certain proportion of rare individuals show natural protection against the viruses. The induction of the innate immune mechanisms is not pathogen-specific but depends on interactions between the host cell…

read more

Healthy Aging with HIV

Although early mortality is delayed because of effective combination antiretroviral therapy (cART), people living with HIV (PLWH) need to take medication life-long. The cART has also shifted the spectrum of morbidity towards non-infectious complications such as ….

read more

HIV-1 drug resistance and treatment response

Antiretroviral therapy (ART) has led to a considerable decrease in AIDS mortality. The emergence of the primary and acquired drug resistance mutations (DRM) poses a significant threat to successful antiretroviral therapy (ART) against HIV-infection.

read more

COVID-19 Research

Viruses exploit the host metabolic machinery to meet their biosynthetic demands, making these host pathways potential therapeutic targets. We are interested in understanding how SARS-CoV-2 rewire host cell metabolism to facilitate optimal viral replication that …

read more

About Research Group

The Neogi Research lab aims to identify the molecular mechanism and identify novel biomarkers of natural immune control against viral diseases and immune aging. We aim to identify the components of the immune response that are required for natural immune protection and disease severity that can be translated into the future development of vaccine and antiviral strategies against emerging and re-emerging viruses like human immunodeficiency viruses (HIV), Crimean–Congo hemorrhagic fever (CCHF) viruses, dengue viruses, Zika viruses.
read more


Publications

69 Publications

View all Publications

Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long term suppressive antiretroviral therapy. Front. Immunol.2019 Aug 27;10:1965.

Babu H, Ambikan AT, Gabriel EE, Svensson-Akusjärvi S, Palaniappan AN, Sundaraj V, Muppani NR, Sperk M, Cheedarla N, Sridhar R, Tripathy SP, Nowak P, Hanna LE†, Neogi U† (2019)

HIV-1 subtype C with PYxE insertion has enhanced binding of Gag-p6 to host cell protein ALIX and increased replication fitness. J Virol. Feb 13. pii: JVI.00077-19. doi: 10.1128/JVI.00077-19. [PMID: 30760577]

van Domselaar R, Njenda DT, Rao R, Sönnerborg A, Singh K, Neogi U† (2019)

Unique phenotypic characteristics of recently transmitted HIV-1 subtype C envelope glycoprotein gp120: Use of CXCR6 co-receptor by transmitted founder viruses. J Virol. 92(9). Pii:e00063-18. [PMID: 29491151]

Ashokkumar M, Aralaguppe SG, Tripathy SP, Hanna LE†, Neogi U†.(2018)


Transcriptomics and targeted proteomics analysis to gain insights into the immune-control mechanisms of HIV-1 infected Elite Controllers. EBioMedicine 27:40-50. [PMID: 29269040]

Zhang W*, Ambican AT*, Sperk M*, Domselaar R, Nowak P, Noyan K, Russom R, Sönnerborg A, Neogi U† (2018)


Virological failure in patients with HIV-1 subtype C receiving antiretroviral therapy: an analysis of a prospective national cohort in Sweden. Lancet HIV3(4):e166-74 [PMID: 27036992]

Häggblom A, Svedhem V, Singh K, Sönnerborg A, Neogi U† (2016)

Dr. Ujjwal Neogi

Biography

Across the globe, there are 37.9 million persons living with HIV (PLWH). With access to antiretroviral therapy (ART), AIDS can be prevented, but the life expectancy for the PLWH is still shorter than in uninfected persons.They often suffer from age-related maladies which diminish their quality of life.                                                                                       View all

  1. June 2013

    PHD

    Karolinska Institute, Stockholm Sweden
  2. July 2007

    MSc

    Bangalore University, Bangalore, India
  3. July 2005

    BSc

    Maulana Azad College, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India